NEW YORK (GenomeWeb News) – A team of researchers from the University of Washington has developed a technique for mapping regulatory protein occupancy across the genome, without prior knowledge of the specific proteins involved.

The approach, which they dubbed "digital genomic footprinting" relies on a combination of DNase I cleavage and high throughput, massively parallel sequencing. The team applied their genomic footprinting to the model organism Saccharomyces cerevisiae, or baker's yeast, identifying thousands of proposed protein binding regions in the genome.

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Apr
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This online seminar will review case studies demonstrating the clinical utility of CTCs and cfDNA to define and characterize a variety of dynamic genomic changes throughout the course of cancer detection and treatment.