By Monica Heger

Spurred by a recent study that used sequencing to determine that GlaxoSmithKline's Rotarix vaccine for rotavirus contained fragments of a porcine circovirus, the Food and Drug Administration's Vaccine's and Related Biological Products Advisory Committee met last week to discuss whether the FDA should advise clinicians to discontinue the use of the vaccine, and how next-generation sequencing could be used as a quality-control measure for vaccines and the cell substrates used in their production.

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