Skip to main content
Premium Trial:

Request an Annual Quote

Exosome Diagnostics, German University Receive €1M Grant to Develop Cancer Dx Tests


Exosome Diagnostics and the department of dermatology at the Ludwig Maximilian University in Munich have been awarded a €1 million ($1.3 million) grant from the German government to develop diagnostic cancer tests based on RNA from plasma-derived exosomes.

Under the grant, from the German Federal Ministry for Education and Research, the researchers plan to develop diagnostic technology to detect tumor-specific mutations in the blood of patients with malignant cancer in order to monitor disease recurrence, aid therapy selection, and possibly improve early tumor detection. The partners plan to couple exosome-based technology with next-generation sequencing and qPCR instrument platforms.

Exosome Diagnostics plans to offer clinical diagnostic tests developed under the project commercially at its laboratories in St. Paul, Minn., and Munich.

Microvesicles, which include exosomes, contain large quantities of tumor-derived mRNA found in biofluids outside of tumor cells. They provide a stable source of RNA in blood, urine, and spinal fluid.

The company has been developing a multiplexed sequencing method for mRNA from blood and urine exosome preparations, which allows for the sensitive detection of rare gene mutations.

The Scan

Unique Germline Variants Found Among Black Prostate Cancer Patients

Through an exome sequencing study appearing in JCO Precision Oncology, researchers have found unique pathogenic or likely pathogenic variants within a cohort of Black prostate cancer patients.

Analysis of Endogenous Parvoviral Elements Found Within Animal Genomes

Researchers at PLOS Biology have examined the coevolution of endogenous parvoviral elements and animal genomes to gain insight into using the viruses as gene therapy vectors.

Saliva Testing Can Reveal Mosaic CNVs Important in Intellectual Disability

An Australian team has compared the yield of chromosomal microarray testing of both blood and saliva samples for syndromic intellectual disability in the European Journal of Human Genetics.

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.