NEW YORK (GenomeWeb News) – A new study is adding heft to the notion that cytoskeletal pathway alterations can spur amyotrophic lateral sclerosis, or ALS, commonly known as Lou Gehrig's Disease.

An international effort spearhead by investigators at the University of Massachusetts used exome sequencing to look for genetic glitches behind an inherited form of ALS, which accounts for around 10 percent of ALS cases.

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In PNAS this week: co-evolutionary signatures of insect hosts and bacterial symbionts, distinct transcript isoforms of high-grade ovarian cancer, and more.

Adam Rutherford discusses genetic genealogy at the Guardian.

Portions of the US 21st Century Cures Act are raising some safety concerns.

David Dobbs writes at Buzzfeed that genomics has delivered little on its promises.