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Erasmus MC Will Automate Exome Capture of 3,000 Samples for Epidemiology Study

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Erasmus University Medical Center in Rotterdam, the Netherlands, is using Caliper Life Sciences' Sciclone NGS Workstation and Roche's NimbleGen SeqCap EZ Exome to automate exome capture and sequencing of more than 3,000 samples, the partners said this week.

The sequencing is being done as part of the Rotterdam Study, a large epidemiological study that includes 15,000 participants to identify genetic risk factors for age-related disorders such as osteoporosis, cardiovascular disease, Alzheimer disease, and type 2 diabetes.

Due to the automation, the Erasmus team expects to complete this portion of the study in the next three to four months. It was "the most optimal solution to analyze these thousands of DNA samples," André Uitterlinden, head of the genetic laboratory at Erasmus MC, said in a statement.

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