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Epicentre Biotechnologies, SoftGenetics, Ensembl 43, PAMGO

Epicentre Biotechnologies has released BACMAX96, a DNA purification kit that can purify 384 fosmids or BACs in less than four hours in a 96-well-format. According to the company, the BACMAX96 kit consistently yields up to 900 nanograms of DNA from single-copy BAC and fosmid clones, and from 2.5 micrograms to 6 micrograms of DNA from the company’s CopyControl BAC and fosmid clones induced to high copy number. The company said it uses an autoinduction protocol specifically designed for high-throughput formats to improve yields from the CopyControl clones.

SoftGeneticsGeneMarker fragment analysis software now includes a new application for loss of heterozygosity analysis. GeneMarker directly processes electrophoretic separation data, performs sizing calculations, normalizes the data, detects areas of LOH, and provides researchers and clinicians with a patient report, the company said.

Ensembl 43 is available here. The release includes genome sequence data for four new species: cat, tree shrew, hedgehog, and guinea pig; a new cow assembly and genebuild; updates for the human and mouse databases; and new variation data for human, rat, and mouse.

The PAMGO consortium has released 472 new terms to describe gene products involved in microbial-host interactions. The new PAMGO terms are available under “multi-organism processes” in the AmiGO Gene Ontology browser. PAMGO was formed to develop new GO terms that describe processes, functions, and cellular components related to microbe-host interactions. Further information about the PAMGO effort is available here.

The Scan

Support for Moderna Booster

An FDA advisory committee supports authorizing a booster for Moderna's SARS-CoV-2 vaccine, CNN reports.

Testing at UK Lab Suspended

SARS-CoV-2 testing at a UK lab has been suspended following a number of false negative results.

J&J CSO to Step Down

The Wall Street Journal reports that Paul Stoffels will be stepping down as chief scientific officer at Johnson & Johnson by the end of the year.

Science Papers Present Proteo-Genomic Map of Human Health, Brain Tumor Target, Tool to Infer CNVs

In Science this week: gene-protein-disease map, epigenomic and transcriptomic approach highlights potential therapeutic target for gliomas, and more