Epicentre Biotechnologies has released BACMAX96, a DNA purification kit that can purify 384 fosmids or BACs in less than four hours in a 96-well-format. According to the company, the BACMAX96 kit consistently yields up to 900 nanograms of DNA from single-copy BAC and fosmid clones, and from 2.5 micrograms to 6 micrograms of DNA from the company’s CopyControl BAC and fosmid clones induced to high copy number. The company said it uses an autoinduction protocol specifically designed for high-throughput formats to improve yields from the CopyControl clones.
SoftGenetics’ GeneMarker fragment analysis software now includes a new application for loss of heterozygosity analysis. GeneMarker directly processes electrophoretic separation data, performs sizing calculations, normalizes the data, detects areas of LOH, and provides researchers and clinicians with a patient report, the company said.
Ensembl 43 is available here. The release includes genome sequence data for four new species: cat, tree shrew, hedgehog, and guinea pig; a new cow assembly and genebuild; updates for the human and mouse databases; and new variation data for human, rat, and mouse.
The PAMGO consortium has released 472 new terms to describe gene products involved in microbial-host interactions. The new PAMGO terms are available under “multi-organism processes” in the AmiGO Gene Ontology browser. PAMGO was formed to develop new GO terms that describe processes, functions, and cellular components related to microbe-host interactions. Further information about the PAMGO effort is available here.