NEW YORK – The window during which human embryos can implant into the endometrium opens with an abrupt change in gene expression of endometrial cells, a new single-cell transcriptomic study has found.
During the human menstrual cycle, the endometrium goes through a process of remodeling, shedding, and regeneration. Because of its important function in human fertility and regenerative medicine, researchers led by Stanford University's Stephen Quake sought to characterize its gene expression at the single-cell level.