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Dolomite Bio, S2 Genomics Collaborate on Automated Single Cell Library Prep From Tissues

NEW YORK – Dolomite Bio and S2 Genomics today announced a collaboration to automate library preparation of tissue samples for single-cell RNA sequencing.

Under the terms of the agreement, the firms will combine the automated solid tissue preparation capabilities of S2 Genomics' Singulator instrument with Dolomite Bio's Nadia single-cell sample prep platform.

Financial and other details were not disclosed.

"Current methods of cell isolation represent a significant bottleneck for researchers and lead to inconsistencies in their data. The Singulator, in combination with the Nadia system from Dolomite Bio, will standardize workflows and optimize the quality of single-cell and single-nuclei data from a variety of solid tissue types," Stevan Jovanovich, president and CEO of S2 Genomics, said in a statement. "This collaboration supports S2 Genomics' mission to develop tools that enable the advancement of single cell biology research and future clinical applications of single cell technologies."

Singulator is a research-use-only sample prep platform that Livermore, California-based S2 Genomics is planning to launch early next year.

UK-based Dolomite Bio sells the microfluidic Nadia platform, which offers fully automated single-cell encapsulation to run the Drop-Seq protocol for single-cell RNA sequencing.

In 2018, Dolomite Bio signed a collaboration agreement with Partek to develop a data analysis pipeline for the Nadia platform.

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