NEW YORK – A new method developed at Sweden's Karolinska Institute offers whole-genome sequencing and transcriptomics for the same single cells, with potential applications in cancer research and genetic screens.
Direct nuclear tagmentation and RNA sequencing (DNTR-seq) is a plate-based method developed by Karolinska cancer research Martin Enge that combines low-coverage sequencing with SMART-seq (switching mechanism at 5' end of RNA template sequencing).
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