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DNAStar, Invitrogen, NCBI

DNAStar has launched SeqMan Genome Assembler, “the first commercially available software tool that permits the assembly of fragment data sequenced using 454, Illumina, and traditional Sanger technologies,” the company said. SeqMan Genome Assembler integrates with DNAStar’s existing Lasergene suite of sequence analysis software, allowing users to perform assemblies and analyses on Windows and Macintosh desktop computers.

Invitrogen has released Dynabeads MyOne Silane and two kits, Dynabeads Silane viral NA and Dynabeads Silane genomic DNA, to support the isolation of low titers of viral RNA and DNA, and pure genomic DNA of high integrity, respectively. The magnetic beads can be used for both high sensitivity in vitro diagnostic assays and high capacity applications and are uniform in size range distribution, surface area, and binding capacity.


GenBank release 163.0 is now available via FTP from the National Center for Biotechnology Information. Uncompressed, the flatfiles require roughly 314 GB (sequence files only) or 335 GB (including the 'short directory', 'index' and the *.txt files). The ASN.1 data require approximately 289 GB. The latest release contains 80,388,382 entries and 83,874,179,730 base pairs.

The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.