DNA Repair Technique Enabled Researchers to Sequence Ancient Hominin Genome, Detect Methylation | GenomeWeb

By Monica Heger

Using a new method to remove deaminated cytosines and repair ancient DNA, researchers from the Max Planck Institute were able to sequence the nuclear genome of an ancient hominin found two years ago in the Denisova Cave in Siberia.

Svante Pääbo, who led the team, announced the preliminary results of the sequencing project at Cold Spring Harbor Laboratory's Biology of Genomes meeting earlier this month. The ancient human appears to represent a new hominin species, Pääbo said.

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