By exploiting sequence and read depth signals that reflect degradation, damage, and protection in ancient DNA, a Danish-led team has come up with treatment-free methods for profiling genome-wide methylation and nucleosome packaging patterns in ancient genomes.

The approaches rely on read depth and deamination profiles to reveal nucleosome occupancy and cytosine methylation, respectively, rather than sequencing DNA treated with nucleases or bisulfite.

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In Genome Research this week: multiplex genotyping of germline and somatic short tandem repeats, graph-based regularization, and more.

A lack of funding may lead more than two dozen research facilities in Australia to shut down in three months.

Researchers report that paternally inherited genes are more likely to be expressed in mice.

The US Supreme Court has declined to review a decision involving the use of "inadvertently shed" DNA in a police investigation and subsequent conviction.