NEW YORK – A team of researchers from China and the US has identified microbial community and metabolite shifts in individuals with major depressive disorder (MDD), along with a set of half a dozen gut microbe and metabolite markers characterizing their disease.
"Our findings lay the foundation for understanding the roles of the overall gut ecosystem in MDD pathogenesis and may facilitate developing objective MDD diagnostic methods," co-corresponding authors Peng Xie, Gang Wang, and Shaohua Hu and their team wrote.