Decode-led Team Uncovers Elevated De Novo Mutation Rate in Children of Older Fathers | GenomeWeb

NEW YORK (GenomeWeb News) – Children born to older fathers tend to have more de novo mutations in their genomes than those with younger dads, according to a study by researchers at Decode Genetics, the University of Iceland, and Illumina Cambridge.

"When we started to look at variation in mutation rates in the population, about 97 percent of it is accounted for by the age of the father," senior author Kari Stefansson, Decode's founder and CEO and a researcher with the University of Iceland, told GenomeWeb Daily News.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

In Science this week: Neanderthal-derived DNA linked to modern ailments, and more.

Japan needs to catch up on its gene-editing research efforts, the Japan News writes.

Hundreds of people have signed an online petition calling for zero tolerance to sexual harassment in the sciences.

Jeff Huber, former Google X senior vice president, joins Grail as its CEO.

Feb
25
Sponsored by
Omicia

This webinar will demonstrate how ACMG's recommended variant scoring and classification rules may be applied to standardize reporting on sequencing test results within and across institutions. 

Mar
03
Sponsored by
Agilent Technologies

This webinar will discuss the use of a hybrid capture-based FFPE DNA sequencing methodology with the potential for advancing precision oncology studies. 

Mar
17
Sponsored by
Qiagen

This webinar will discuss Qiagen's approach to address two challenges facing NGS in the clinical research setting: lack of seamless workflow for routine clinical research use and truly relevant content to guide clinical research activities.