Cornell Study Shows Targeted Sequencing Can ID Mutations in Advanced Prostate Cancer FFPE Samples | GenomeWeb

Collaborating with Foundation Medicine, researchers from Weill Cornell Medical College have demonstrated that targeted sequencing can identify potentially actionable mutations in formalin-fixed paraffin-embedded samples from advanced prostate cancers.

The group published in the Journal of the European Association of Urology this month results of a small study that sequenced samples from 45 patients. Sequencing the samples to an average depth of 900x yielded a number of potentially targetable mutations, including a novel rearrangement involving BRAF.

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In Nature this week: genome-wide transcriptome analysis of brain samples from people with autism spectrum disorder, flounder genome, and more.

Researchers used T-cell transfer therapy to target mutation KRAS, according to the New York Times.

The US Senate has passed the 21st Century Cures Act, which would provide a funding boost at NIH while overhauling FDA policies.

Bloomberg reports that President-elect Donald Trump is considering Jim O'Neill for Food and Drug Administration commissioner.