A Copy-Number Lesson


Sometimes a project doesn't quite produce expected results. In their search for copy-number variants associated with Parkinson's disease, Nathan Pankratz and his colleagues thought at first that they'd uncovered new CNVs, but those findings did not hold up under further scrutiny. "We thought that we had a couple of good leads in the current study but when we tried to validate them molecularly, it failed," says Pankratz, who was at Indiana University School of Medicine at the time.

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