Investment firm William Blair and Company began covering Pacific Biosciences this week with a "Market Perform" rating, but estimated that sales of the company's RS machine will be slightly below consensus estimates.

The firm predicted PacBio will ship 46 instruments in 2011, 125 in 2012, and 170 in 2013, which is 99 fewer total instruments than the 440 machines analysts previously predicted PacBio will ship by 2013.

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Researchers have treated an X-linked genetic disease affecting three babies in utero, Stat News reports.

The Associated Press reports that the US Centers for Disease Control and Prevention is beefing up sequencing as a tool to investigate foodborne illnesses.

Researchers have sequenced samples from ancient toilets to study past eating habits and health, NPR reports.

In Nature this week: ash dieback disease fungal genome, and more.

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