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Clinical Sequencing Papers of Note: Jul 6, 2011


Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer.
Kim JH, Dhanasekaran SM, Prensner JR, et al.
Genome Res. 2011 Jul;21(7):1028-41.

Integrated genomic analyses of ovarian carcinoma.
The Cancer Genome Atlas Research Network
Nature. 2011 Jun 29;474(7353):609-615.

RNA is favorable for analyzing EGFR mutations in malignant pleural effusion of lung cancer.
Tsai TH, Su KY, Wu SG, et al.
Eur Respir J. 2011 Jun 30. [Epub ahead of print]

Next-generation sequencing of microRNAs for breast cancer detection.
Wu Q, Lu Z, Li H, Lu J, Guo L, Ge Q.
J Biomed Biotechnol. 2011;2011:597145.

Evaluation of high throughput sequencing for identifying known and unknown viruses in biological samples.
Cheval J, Sauvage V, Frangeul L, et al.
J Clin Microbiol. 2011 Jun 29. [Epub ahead of print]

Clinical effect of point mutations in myelodysplastic syndromes.
Bejar R, Stevenson K, Abdel-Wahab O, et al.
N Engl J Med. 2011 Jun 30;364(26):2496-506.

STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis.
van de Veerdonk FL, Plantinga TS, Hoischen A, et al.
N Engl J Med. 2011 Jun 29. [Epub ahead of print]

A mild form of mucopolysaccharidosis IIIB diagnosed with targeted next-generation sequencing of linked genomic regions.
Selmer KK, Gilfillan GD, Strømme P, et al.
Eur J Hum Genet. 2011 Jun 29. [Epub ahead of print]

Pyrosequencing-based methods reveal marked inter-individual differences in oncogene mutation burden in human colorectal tumours.
Weidlich S, Walsh K, Crowther D, et al.
Br J Cancer. 2011 Jun 28. [Epub ahead of print]

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