Skip to main content

Cincinnati Children's Hospital, UC Develop Software for Gene-Variant Research

NEW YORK (GenomeWeb News) — Cincinnati Children’s Hospital Medical Center and the University of Cincinnati’s Computational Medicine Center have developed software to help researchers decide if changes in genomic sequences may be related to disease or whether they warrant further study, the hospital said today.
Developed with funding from the National Institute of Environmental Health Sciences and the National Cancer Institute, the software, called PolyDoms, is a web-based tool that will “help prioritize which genetic variations are more likely to alter the structure and function of a protein,” said David Schwartz, director of the NIEHS.
Knowing those variations, Schwartz said, will provide researchers “with critical information related to disease susceptibility, progression and targets for therapeutic interventions.”
The PolyDoms software may be accessed freely here.

The Scan

UK Funds to Stay Ahead of Variants

The UK has announced a further £29.3 million to stay on top of SARS-CoV-2 variants, the Guardian reports.

Push for Access

In a letter, researchers in India seek easier access to COVID-19 data, Science reports.

Not as Cold

Late-stage trial results are expected soon for an RNA-based vaccine that could help meet global demand as it does not require very cold storage, the New York Times writes.

Genome Research Papers on Microbes' Effects on Host Transfer RNA, Honeybee Evolution, Single-Cell Histones

In Genome Research this week: influence of microbes on transfer RNA patterns, evolutionary relationships of honeybees, and more.