By Julia Karow

As Illumina sequencers in particular, as well as the 454 platform, have become the workhorses for a variety of sequencing projects at the Broad Institute, its scientists have fine-tuned their sample-prep methods to keep the machines fed at all times.

At the Evolution of Next-Generation Sequencing conference in Providence last month, two members of the Broad's process development team shared some of the changes that have made sample prep faster, cheaper, and more high-throughput.

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