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Broad Institute Purchases Fluidigm Access Array for Targeted Resequencing Sample Prep


This article was originally published May 26.

The Broad Institute has purchased Fluidigm's Access Array System, which it will use to automate sample prep for targeted resequencing, the company said last week.

The platform allows users to PCR-amplify 48 samples in parallel and combines target enrichment, sample barcoding for multiplexed sequencing, and library preparation using amplicon tagging.

The system includes single-use microfluidic integrated fluidic circuits chips, two IFC controllers to load the arrays, and a standalone thermal cycler. Fluidigm offers customers primer design services for human targeted resequencing.

The Access Array currently supports Life Technologies' SOLiD, Illumina's GA and HiSeq sequencers, Roche 454's GS FLX and GS Junior, and Pacific Biosciences' RS. Fluidigm plans to make it compatible with the Ion Torrent PGM and the Illumina MiSeq (IS 5/17/2011).

The Scan

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The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.