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NEW YORK (GenomeWeb) – New research suggests that common and rare genetic variants — and past treatment exposures — can all contribute to breast cancer risk in women who survived cancer as a child.

As part of the St. Jude Lifetime Cohort Study, investigators from St. Jude Children's Research Hospital and other centers in the US and Canada used whole-genome sequencing to profile germline variants in more than 1,100 women of European ancestry who survived childhood cancer, searching for germline differences in the 47 women who were subsequently diagnosed with breast cancer.

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In PLOS this week: computational strategy for improving gene set analysis testing, miRNAs linked to sleep apnea, and more.

Mar
21
Sponsored by
Loop Genomics

This webinar provides a comparison of next-generation sequencing (NGS) approaches for human transcriptome sequencing, including short-read Illumina sequencing and synthetic long-read sequencing technology.

Mar
26
Sponsored by
PerkinElmer

This webinar will address the current status and future directions for massively high-throughput genomics for plant and animal breeding and research.

Mar
27
Sponsored by
Swift Biosciences

Sequencing workflows require library quantification and normalization to ensure data quality and reduce cost. 

Mar
28
Sponsored by
Qiagen

The Human Gene Mutation Database (HGMD) is a manually curated, comprehensive collection of disease-causing, germline mutations. Since 1996, a team of experts has manually catalogued over a quarter of a million mutations for the database.