By Monica Heger

This story was originally published Feb. 9.

Pacific Biosciences booked six new RS instruments in the fourth quarter of 2011— one fewer than it booked in the third quarter — and installed 17 systems, company officials said last week during a conference call to discuss the company's fourth-quarter and full-year earnings.

The company has a current backlog of 16 systems, representing $11 million in revenue, and has a total of 48 systems installed, officials said.

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In Science this week: mtDNA analysis give glimpse into decline of Neanderthals in Europe, and more.

The University of Arizona's Raina Maier writes that an understanding of the Earth's microbiome is needed.

The proposed Canadian budget emphasizes partnerships with industry, Nature News reports.

An Australian study of personalized medicine has run into problems as it recruits patients.

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