Bioinformatics Groups Tackle Challenge of De Novo Assembly Using Microread Data | GenomeWeb
Two next-generation sequencing platforms currently hitting the market, Illumina’s Genetic Analyzer and Applied Biosystems’ SOLiD technology, generate so-called “microreads” of currently around 30 base pairs — a constraint that has so far excluded their use alone in de novo genome assembly, and limited their application mostly to resequencing projects in which the short reads are aligned to a reference genome.

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