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BGI to Sequence 100 Vertebrate Species for Genome 10K Project

By Andrea Anderson

COLD SPRING HARBOR, NY (GenomeWeb News) – Researchers at BGI plan to sequence 100 vertebrate genomes in two years or less as part of an international Genome 10K project, BGI President Huanming "Henry" Yang announced at the Biology of Genomes meeting here today.

Yang said BGI will tackle the first 100 genomes of the Genome 10K — an international effort gearing up to sequence 10,000 vertebrate species — at its facilities in China.

BGI will use the Illumina HiSeq 2000 platform for the vertebrate sequencing effort, according to Stephen O'Brien, a geneticist at the National Cancer Institute, chief of NCI's genomic diversity laboratory, and one of the Genome 10K project leaders.

Early this year, Illumina announced that BGI had purchased 128 of the new HiSeq 2000 instruments and plans to install them this year.

Species to be sequenced will be selected based on phylogenetic diversity, sample availability, biological relevance, and so on. But Yang said BGI is also seeking input from the research community in selecting the species, noting that a Genome 10K workshop will be held in Santa Cruz, Calif., next March.

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