Skip to main content
Premium Trial:

Request an Annual Quote

Baylor to Sequence More than 5,000 Exomes for Human Disease Studies

Premium

The Human Genome Sequencing Center at Baylor College of Medicine plans to use Roche NimbleGen exome capture products as part of an effort to sequence more than 5,000 human exomes over the next two years to discover genetic variants underlying a number of human diseases, the company said this week.

Funded by the National Institutes of Health and several research consortia, Baylor researchers plan to study more than 15 diseases by exome sequencing, including cancer of the brain, liver, pancreas, colon, ovary, and bladder; heart disease; diabetes; autism; and several inherited diseases.

The center will use both NimbleGen's SeqCap EZ Exome and customized NimbleGen exome designs in these studies, according to the company. In collaboration with Roche NimbleGen, it has established a pipeline for high-throughput exome capture and sequencing “with multiple next-generation sequencing platforms.”

Baylor has already sequenced the exomes of approximately 1,000 samples, and captured and sequenced DNA from about 1,000 additional samples, according to NimbleGen.

The Scan

Just Breathing

A new analysis suggests that most Mycobacterium tuberculosis is spread by aerosols from breathing, rather than by coughing, the New York Times reports.

Just Like This One

NPR reports that the World Health Organization has hired a South African biotech company to recreate mRNA vaccine for SARS-CoV-2 that is similar to the one developed by Moderna.

Slow Start

The Wall Street Journal reports that Biogen's Alzheimer's disease treatment had revenues for July through September that totaled $300,000.

Genome Research Papers on Cancer Chromatin, Splicing in the Thymus, Circular RNAs in Cancer

In Genome Research this week: analysis of bivalent chromatin sites, RBFOX splicing factors' role in thymic epithelial cells, and more.