SAN DIEGO (GenomeWeb) – Whether to use a gene panel or sequence the entire exome is an ongoing debate with each option having its own advantages and drawbacks and also depending on the disorder being studied, researchers said at the American Society of Human Genetics meeting, held here this week.

While exome sequencing is more comprehensive than gene panels, it may add to cost and may not even completely cover the genes of interest. However, even in well-phenotyped cases, exome sequencing can uncover an unexpected molecular diagnosis.

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Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.

Retraction Watch's Ivan Oransky and Adam Marcus report that Harvard Medical School and Brigham and Women's Hospital have recommended that more than 30 papers from a former researcher be retracted.

Thomas Steitz, who won the 2009 chemistry Nobel Prize for his ribosome work, has died, the Washington Post reports.

In PLOS this week: mechanisms for genes implicated in coronary artery disease, rumen microbes and host genetics influence cow methane production, and more.