NEW YORK (GenomeWeb) – Researchers from the US, Japan, and Bangladesh have identified gut microbial community shifts in children who are prone to severe cases of amebic dysentery caused by Entamoeba histolytica infections.

The investigators used 16S ribosomal RNA sequencing on stool samples from dozens of children from birth cohorts in Dhaka, Bangladesh to tally up and compare gut microbial diversity in children without E. histolytica infections, with asymptomatic E. histolytica infections, and in those with serious complications such as amebic colitis.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

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In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.

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