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Advanced Analytical, TTP Labtech Ink Comarketing Agreement for NGS Library Prep

NEW YORK (GenomeWeb) – Advanced Analytical Technologies (AATI) and TTP Labtech announced today that they have signed a comarketing agreement. The partnership combines TTP's Mosquito and AATI's Fragment Analyzer platforms to reduce cost, maximize throughput, and improve quality of next-generation sequencing library preparation.

TTP Labtech produces products for sample management, liquid handling and multiplexed detection in drug discovery and genomics, while AATI creates low- and high-throughput automated analysis systems.

"This partnership with TTP Labtech is enabling high-throughput NGS discovery with robust miniaturization and accurate quantification on the Fragment Analyzer," Jonathan Hagopian, director of business development at AATI, said in a statement.  

"TTP Labtech and Advanced Analytical instruments, together, provide powerful cost-effective genomics workflow solutions," Klaus Hentrich, genomics product manager at TTP Labtech, added.

Researchers from Stanford University have already combined the two technologies to overcome challenges associated with high-throughput single-cell sequencing, work that they published last year in Cell and Nature Scientific Data. They were working on mapping stem cell differentiation along multiple mesodermal lineages which required preparation of miniaturized RNA-seq libraries from nearly a thousand single cells.

"This semi-automated, robust SMART-seq2 workflow for single-cell RNA-seq has reduced our hands-on time from two weeks to a couple of days, while increasing the accuracy and lowering the cost," Rahul Sinha, a researcher in the Irving Weissman Lab at Stanford, said in a statement. "The AATI Fragment Analyzer and TTP Labtech's mosquito X1 and mosquito HTS have been essential for this new workflow."

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