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454, Baylor Complete Sequence of Watson's Genome; Cost Breaks $1M Mark

NEW YORK (GenomeWeb News) — 454 Life Sciences and the Human Genome Sequencing Center at Baylor College have finished sequencing, verifying, and annotating the genome of James Watson, the partners said today.
 
The project took two months and cost less than $1 million, the first human genome to break the $1 million mark, the company and the school said. 454 handled the sequencing and BCM verified and interpreted the data, Baylor said.
 
Michael Egholm, 454’s vice president of R&D, said the company performed the sequencing on its GS FLX systems and obtained “a near complete picture” of Watson’s genome. He also said the project identified “missing pieces of the public reference genome” generated by the Human Genome Project.
 
Watson will receive the sequence on a DVD at an event today at Baylor’s campus that will include speeches by Watson and representatives of 454 and BCM. He will decide what portions of his genomic information will be made public.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.