NEW YORK (GenomeWeb) – Researchers with the PATHSEEK consortium have developed a method to quickly sequence Mycobacterium tuberculosis from sputum samples, rather than having to wait the weeks it can take to culture bacterial samples.

By using biotinylated RNA baits to grab full M. tuberculosis sequences from their samples, the researchers reported in the Journal of Clinical Microbiology today that they could generate sequences and analyze them for drug-resistance genes within a clinically relevant timeframe of up to 96 hours.

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In Genome Research this week, mismatch repair deficiency in C. elegans, retracing transcriptions start site evolution in the human genome, and more. 

May
01
Sponsored by
Horizon Discovery

This webinar will provide an in-depth case study demonstrating how reference standards can be used to develop and validate circulating tumor DNA (ctDNA)-based assays.

May
03
Sponsored by
Canon BioMedical

This webinar will introduce new technologies that enable multidimensional measurements from single cells to obtain a more complete picture of a cell’s phenotype and gene expression.

May
08
Sponsored by
Dovetail Genomics

This webinar will discuss a proximity ligation-based method for studying structural variation in formalin-fixed paraffin-embedded (FFPE) tissue.

May
10
Sponsored by
NuGEN

This webinar will highlight the use of high-throughput sequencing of post-mortem human brain tissue to identify neurodegenerative markers and identify potential drug targets.