NHGRI Working Group Says Labs, Clinicians Should Include Germline Variants in Tumor Sequencing Tests | GenomeWeb

NEW YORK (GenomeWeb) – Most genomic sequencing-based cancer tests currently do not analyze germline DNA, focusing instead on tumor tissue to keep costs down and speed up turnaround time, despite the fact that studies have shown that this practice may lead to missed results. Nevertheless, it is still possible to identify cancer risk variants that originate in the germline solely from cancer tissue, and laboratories should be prepared to deal with such findings, according to a National Human Genome Research Institute and National Cancer Institute working group.

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Feb
23
Sponsored by
NuGEN

This webinar will discuss a project that sought to understand the parent-of-origin epigenetic mechanisms that regulate seed development in plants, with a particular emphasis on differentiating the maternal or paternal origin of epigenetics marks.

Mar
02
Sponsored by
VelaDx

This online seminar will highlight recent advances in the use of next-generation sequencing to detect drug-resistant mutations in patients with HIV or HCV.