NEW YORK (GenomeWeb) – Two recently published sequencing methods demonstrate the ability to systematically reveal unintended consequences of CRISPR/Cas9 activity in the genome.

The methods could provide researchers with an accurate and unbiased tool to gauge the specificity of the gene editing technology as it moves closer toward clinical therapeutic use, according to experts.

The ability of the Cas9 nuclease to create a double-stranded break is the crux of CRISPR, but scientists have been reporting off-target effects and have to design their experiments to account for it.

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Bavaria expands its forensic genetic analyses to include DNA phenotyping, raising discrimination concerns.

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Jun
12
Sponsored by
Philips Genomics

This webinar will highlight a comprehensive end-to-end solution for precision care in oncology, comprising sample acquisition through to sequencing and analysis, treatment recommendations, and follow-through.

Jun
14
Sponsored by
Sophia Genetics

This webinar will discuss an effort underway at the University of North Carolina Medical Center's to overcome limitations in the hematological genomic testing workflow with artificial intelligence (AI) from Sophia Genetics.

Jun
19
Sponsored by
Advanced Cell Diagnostics

This webinar will provide evidence for the use of RNA in situ hybridization (RNA ISH) as a replacement for immunohistochemistry (IHC) in cancer research and diagnostic applications.

Jun
20
Sponsored by
PerkinElmer

In this webinar, Michael Quail of the R&D Sequencing team at the Wellcome Trust Sanger Institute will provide an expert perspective on library prep for next-generation sequencing.