Skip to main content
Premium Trial:

Request an Annual Quote

Cancer Research UK, Illumina Ink Sequencing Tech Supply Deal for Lung Cancer Trial

NEW YORK (GenomeWeb) – Cancer Research UK today announced it has signed a supply agreement with Illumina to use the firm's sequencing technology in a large British lung cancer clinical trial that aims to advance personalized medicine.

Under the terms of the agreement, Illumina will provide its research-use-only Nextera Rapid Capture Enrichment kits and NGS technology to a multi-arm, early-stage clinical trial — called the National Lung Matrix Trial — being run by Cancer Research UK.

"This is one of the largest ever personalized medicine trials in any cancer, one which attempts to match the right treatments to the right patient based on an in-depth understanding of what makes their own cancer cells grow and survive," Gary Middleton, chief investigator of the National Lung Matrix Trial, said in a statement.

Investigators will sequence a customized set of 28 genes to stratify patients and place them into the most appropriate arm of the trial. AstraZeneca and Pfizer are also partnering with Cancer Research UK to provide the targeted treatments for each arm of the trial.

"Genetic sequencing will provide the information that allows us to routinely pair up patients with this more targeted approach," Ian Walker, head of stratified medicine at Cancer Research UK, said in a statement. "This collaboration will help our researchers to quickly identify the genetic faults underpinning a patient's cancer."

Financial details of the agreement were not disclosed. 

The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.