Sequencing

News on NGS technologies, RNA-seq, clinical sequencing, & sample prep in genetics, genomics, and molecular diagnostics.

Genuity Science, Formerly WuXi NextCode, Reinvents Itself With US, Europe Focus

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Based in Boston with operations in Ireland and Iceland, the reorganized company is supporting COVID-19 testing and population genomics as it sheds its China division.

Paragon Genomics Betting Updated SARS-CoV-2 NGS Kit Will Enable High-Throughput Research, Testing

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Users will be able to sequence over 20,000 samples simultaneously with the updated panel, which the firm expects to offer sometime in the third quarter for research use only.

Prediabetes, Type 2 Diabetes Come With Altered Gut Microbiomes

A new analysis highlighted a decrease in the abundance of butyrate-producing bacteria among individuals with prediabetes or type 2 diabetes.

Study Spells Out Immune, Genomic, Epigenomic Interactions in Hematological Malignancies

Transcriptomic and multi-omic data spanning more than 10,000 samples helped map "immunogenomic" interactions that may inform treatment outcomes and targets.

Dual-Reader Nanopore Promises Improved Homopolymer Sequencing Accuracy

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The new pore, a complex between E. coli CsgG and part of CsgF, called certain homopolymers more accurately than an engineered version of CsgG.

Jul 09, 2020

Integrated Proteomic Papers Define Lung Cancer Features Across Populations, Smoking Histories

Jul 09, 2020

OncoDNA to Acquire IntegraGen for €14.5M

Jul 09, 2020

Aneuploidy Common in Early-Stage Human Embryos, Single-Cell RNA-Seq Study Reveals

Jul 08, 2020

Glioblastoma, Developing Brain Cell Populations Show Similarities in Single-Cell RNA-Seq Study

Jul 07, 2020

Sequencing Study Reveals Role of RIPOR2 Mutation in Adult-Onset Hearing Loss

Jul 07, 2020

Exome Analysis of Southwestern American Indians Highlights Metabolic Disease-Linked Variants

Jul 02, 2020

Translation of Dog Years Into Human Years Updated With Epigenetic Analysis

Jul 02, 2020

Type 2 Diabetes Associated With Altered Daily Gut Microbe Oscillations

Jul 01, 2020

Early-Onset Preeclampsia Risk Reflected in Circulating Maternal Transcripts

Jul 01, 2020

AnchorDx Demonstrates Liquid Biopsy DNA Methylation Test for Early Cancer Detection

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Jul 01, 2020

Celsius Therapeutics Teams With Oxford, Cleveland Clinic, LMU on Single-Cell IBD Research

Jul 01, 2020

BioSpyder Wins High-Throughput Toxicology Screening Contract From EPA

Jun 29, 2020

Noncoding De Novo Mutations Contribute to Congenital Heart Disease, Sequencing Study Finds

Jun 26, 2020

Single-Cell COVID-19 Study Suggests Chemokine Receptor Inhibition Could Quell Immune Hyperactivation

Jun 26, 2020

Iowa Startup FBB Biomed Pursues RNA Blood Test to Predict COVID-19 Disease Severity

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Jun 26, 2020

Brain, Kidney Cancer Studies Lay Path for Clinical Application of Epigenetic Liquid Biopsy Method

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Jun 25, 2020

At AACR, Stanford Team Shares Single-Cell Fusion Detection Tool For Mapping Tumor Cells

Jun 25, 2020

Inivata Demonstrates Potential of ctDNA Assay for Cancer Recurrence, MRD Applications

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Jun 24, 2020

Stanford Team Debuts EPIC-Seq Method to Detect, Classify Cancer From cfDNA Fragment Patterns

Jun 24, 2020

Whole-Genome Sequencing Study Identifies Four Novel Disease-Causing Variants

The Scan

Cost of Meeting Cancellations

Nature News reports on how meeting cancellations and related costs are affecting scientific societies.

Genetic Nondiscrimination Act Upheld

In a new ruling, Canada's Supreme Court upheld the country's genetic non-discrimination law, the Canadian Press reports.

Enhancement Avoidance

COVID-19 vaccine developers aim to avoid a complication that has affected efforts to develop vaccines for other diseases, the Wall Street Journal reports.

PLOS Papers on Shigella Insertion Sequences, Antigens and Plasmodium vivax Diversity, More

In PLOS this week: analysis of insertions throughout Shigella genomes, antigen production in malaria parasites, and more.

Featured White Papers

White Paper: Using Single-Cell Multiomics to Reveal New Insights Into Uveal Melanoma Evolution and Therapeutic Resistance

AnyDeplete - A customizable depletion solution for RNA-Seq workflows

95 MDAF: Modeling Noise in Archer NGS Data with Per-Base Resolution for Statistically Informed, Position-Dependent Variant Calling

Independent Evaluation of ReproSeq-PGS A GenomeWeb eCase Study Transcript

Jul

15

Featured Webinar

Diagnostic Challenges in Cancer Immunotherapy: An Expert Panel Discussion

Cancer immunotherapy is an exciting new advance for the successful treatment of many forms of metastatic cancer.

Jul

16

Featured Webinar

Exploring Tumor Tissue Architecture and Immune Response with Digital Spatial Profiling

Join this webinar to learn how spatial resolution of gene expression in tumor tissue reveals new insights in biomarker discovery and therapeutic response.

Jul

22

Featured Webinar

Advances in Genetic Testing for IVF Research: PGT-A, PGT-M, and Carrier Screening

Luis A. Alcaraz, cofounder of Bioarray and Journey Genomics, accredited diagnostic and research labs based in Alicante, Spain, will review how his teams use advanced genomic techniques for carrier screening research as well as for preimplantation genetic testing (PGT) in embryos for both aneuploidies (PGT-A) and monogenic disorders (PGT-M).

Jul

29

Featured Webinar

Life Science Marketing Workshop: Creating a Go-To-Market Strategy in a Rapidly Evolving Sector

“If we build it, they will come” is a familiar refrain that echoes in life science entrepreneurial circles. Too frequently startups believe that if a technology is built it will sell.

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