warfarin genotyping

The study, involving 322 patients from China, India, and Malaysia, is the largest randomized evaluation of warfarin PGx in Asian patients, the authors said.

Operating since the beginning of the year in a pilot mode, the company officially launched its comprehensive PGx testing service last week.

A study has demonstrated why dosing algorithms for warfarin have performed poorly in patients with African ancestry, especially in recent randomized clinical trials.

A genome-wide association study by researchers at several US and international institutions has found a novel variant — rs12777823 — that explains some of the variability in warfarin metabolism in African-American individuals and could potentially improve the effectiveness of pha

Nanosphere has raised $26.9 million in a public offering that it expects will see it through the regulatory approval of its infectious disease test pipeline and support additional commercial development to bring the firm to the break-even point.

The eventual goal of the partnership would be to port the validated assay onto Rheonix's fully automated, modular molecular testing platform, which is still under development but may reduce the complexity and cost of warfarin sensitivity testing.

The investment firm lowered revenue estimates and the share-price target for Nanosphere following the FDA's denial of the company's Plavix metabolism test.

Pharmigene now has the global licensing rights to VKORC1-1639 SNP-related patents and application from the University of Washington and Academia Sinica.

PGXL will use AutoGenomics' Infiniti analyzer for various personalized medicine applications. Specifically, PGXL plans to use AutoGenomics' FDA-cleared Infiniti warfarin assay and CYP450 2C19 assay.

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.