variants of unknown significance BRCA2 Variants of Unknown Significance Reclassified Through Functional Data Additions Researchers reclassified 86 percent of variants initially determined to be VUS, potentially changing surveillance or treatment approaches for patients. Qiagen Takes Over Commercial Sales of Sanger's COSMIC Database Premium The partners hope that the relationship will expand the reach of the COSMIC database for somatic tumor mutations while also fine-tuning future technology development. Quest Diagnostics Win in Wrongful Death Case Reveals Ongoing Challenges for Variant Classification Williams v Quest/Athena struck a nerve with the genetic testing community by probing what the standard of care is and ought to be for variant classification. Ancestry Rolls Out Sequencing-Based Health Offering Focused on Common Conditions Premium The next iteration of Ancestry's Health experience seeks to provide customers with actionable information about certain commonly inherited health conditions. Patients Having Ovaries Removed Without Clear Genetic, Medical Rationale, Study Suggests Premium Results from the PROMPT registry presented at ASCO showed that 10 to 15 percent of women with variants in genes not linked to ovarian cancer had oophorectomies. Feb 11, 2020 Quest Files Motion for Summary Judgment in Wrongful Death Lawsuit Jan 9, 2020 With More Than a Million Records, ClinVar Value Grows as Variant Classification Resource Premium Oct 4, 2019 Adding RNA-Seq, Ambry Genetics Expects to Reduce VUS Results in Hereditary Cancer Tests Premium Aug 20, 2019 Genomenon Enters Chinese Market With Shanghai Shanyi Partnership Jun 27, 2019 MedSeq Team Reports Genome Analysis, Reanalysis Results for 100 Participants Jun 4, 2019 Patients With Pathogenic Breast Cancer Variants May Receive Treatment That Deviates From Guidelines Premium Apr 1, 2019 First Epigenetic Signature Test for Inherited Disorders to Launch in the US, Europe Premium Jan 17, 2019 UK Biobank Dataset Helps Elucidate Pathogenicity of Rare Genetic Variants Nov 16, 2018 NSGC: Clinical Variant Interpretation Continues After Lab Reports Issued Nov 6, 2018 Childhood Epilepsy Diagnoses Shift With Genomic Reinterpretation Oct 23, 2018 Quest Diagnostics Wrongful Death Lawsuit Ordered to Move to Discovery Oct 12, 2018 Publications Highlight Findings Emerging From ClinGen Program Sep 12, 2018 Saturation Editing of BRCA1 Exons Reveals Functional, Non-Functional Variants Sep 6, 2018 Sanford Health Lab Aims to Refine Genetic Testing Panels With Genoox Classification Tool Premium Jul 3, 2018 In Williams v Quest, State Supreme Court Leaves Room for Plaintiff to Argue Ordinary Negligence Jun 13, 2018 Researchers Predict Classification of Thousands of BRCA1/2 Missense Variants Using In Silico Models Premium May 10, 2018 Multi-Gene Hereditary Breast Cancer Tests Double Detection Rate; Don't Spur Breast Removal Mar 7, 2018 French Researchers to Assess NovellusDx Assay for Ability to Predict Cancer Treatment Response Premium Feb 28, 2018 Cardiomyopathy Genetic Tests Work Better in White Patients Than Other Ethnicities Feb 16, 2018 South Carolina Supreme Court Mulls Whether Quest is Healthcare Provider in Wrongful Death Suit Load More Breaking News Ancient DNA Analysis Highlights Three Ancestral Populations in Japan FDA Warns of Potential False Positives With Abbott SARS-CoV-2 Molecular Tests New Products Posted to GenomeWeb: Oxford Nanopore, Beckman Coulter, Thermo Fisher Scientific, More People in the News: New Appointments at Sema4, NHGRI, Dante Labs, Ancestry, More Thermo Fisher Scientific Expects 12 Percent Revenue Growth in 2022 In Brief This Week: Myriad Genetics, Danaher, Co-Diagnostics, and More The Scan For Those Thick Tiger Stripes Tigers in India with thick stripes harbor a genetic change, as Gizmodo reports. High GABA Tomatoes The Japan News reports that genome-edited tomatoes with higher GABA levels are now for sale in Japan. Approach for Inclusivity and Diversity A National Human Genome Research Institute team calls for the field to "adopt diversity as an ethos." Science Papers on Tumors Immune System Evasion; Drivers of Genomic Instability, Inflammation In Science this week: study of how tumors evade the adaptive immune system, and more.