telomeres | GenomeWeb

telomeres

Researchers found that telomeres were shorter in tumors than in normal tissues and longer in sarcomas and gliomas than in other cancers.

In Genome Research this week: molecular autopsies for sudden death, telomere methylation in Arabidopsis, and more.

Researchers link telomere length to socioeconomic status and ethnicity.

Researchers at the University of Texas Southwestern Medical Center uncovered variants in two genes tied to pulmonary fibrosis and telomere shortening.

Bio-Rad is working with Elizabeth Blackburn, a researcher at the University of California, San Francisco School of Medicine and co-founder of Telome Health, to develop a sensitive and high-throughput digital PCR assay to measure telomerase activity in human cells, PCR Insider

Telome Health said this week that it plans to launch its qPCR-based TeloTest diagnostic assay for measuring average telomere length in the first quarter of 2013.

Genetic, medical, and environmental data on 100,000 Kaiser Permanente enrollees will become accessible to researchers next year. It will be free to those conducting NIH-funded studies, but others will need to pay a fee.

The assay, which its developers claim can measure telomere length in less than half the time of other PCR-based methods while using 20-fold less genetic material, will be deployed as part of a clinical study designed to monitor changes in telomere length in response to certain therapies in patients with telomere diseases.

The company is using a quantitative PCR method licensed from the University of Utah to measure telomere length from tissue samples for research, drug-development, and health-monitoring applications.

Harold Varmus, a former NIH director, says that proposed reductions to the agency's budget are worrisome.

The Genome 10K project is to sequence about 10,000 vertebrate genomes, including ones of endangered species, Digital Trends reports.

The new Coalition to Save NIH Funding aims to educate lawmakers and the public on the significance of biomedical research.

In PLOS this week: analysis of viral sequences from human blood samples, gut microbiomes of heart failure patients, and more.