Close Menu

Scientific Terms: TCGA

With $200M in new investment, the precision medicine firm has launched a clinical trial matching service, is adding clinical data to TCGA, and is moving into the Asian market.

In Nucleic Acids Research this week: database of methylation quantitative trait loci in tumors, database of ancient mitochondrial genomes, and more.

One of the largest repositories of molecular brain cancer data in the world, the enhanced REMBRANDT is more comprehensive than an earlier NCI-hosted version.

A TWAS in 229,000 women led to 48 genes with apparent links to breast cancer, serving as fodder for additional pathway and functional analyses.

Researchers associated with the Cancer Genome Atlas (TCGA) Research Network will publish more than 25 papers this week to discuss findings from the initiative.

Researchers and clinicians attempting to select targeted therapies must take sample heterogeneity into account.

This Week in Nucleic Acids Research: Researchers describe a new method to find large-scale structural variants in cancer genomes, a glimpse at an approach for profiling miRNAs in tumor samples from TCGA, and more.

NEW YORK (GenomeWeb) – New thyroid cancer mutations reported recently by members of The Cancer Genome Atlas consortium are already finding their way into at least one sequencing-based genotyping test used to distinguish between benign thyroid nodules and thyroid malignancies.

NEW YORK (GenomeWeb) – A Maryland-based team used real-time, quantitative PCR to screen for human papillomavirus in blood and saliva in order to detect HPV-positive head and neck cancers, track their recurrence, and predict survival patterns.

NEW YORK (GenomeWeb) — An analysis of data from The Cancer Genome Atlas' comprehensive molecular profiling of squamous cell head and neck cancer has revealed a more complicated molecular landscape for the disease, and has identified a new genomic subset that indicates particularly poor survival.

Pages

NPR reports the US Food and Drug Administration has approved a treatment for a genetic disorder that causes rapid aging.

Late-stage testing indicates the AstraZeneca and Oxford University SARS-CoV-2 vaccine can have up to 90 percent efficacy, the Associated Press reports.

ScienceInsider reports Nature Communications is reviewing a paper on mentorship following social media criticism arguing it is sexist.

In PLOS this week: method to account for sequencing errors in phylogenies, study of influenza A in Switzerland, and more.