TCGA

A TWAS in 229,000 women led to 48 genes with apparent links to breast cancer, serving as fodder for additional pathway and functional analyses.

Researchers associated with the Cancer Genome Atlas (TCGA) Research Network will publish more than 25 papers this week to discuss findings from the initiative.

Researchers and clinicians attempting to select targeted therapies must take sample heterogeneity into account.

This Week in Nucleic Acids Research: Researchers describe a new method to find large-scale structural variants in cancer genomes, a glimpse at an approach for profiling miRNAs in tumor samples from TCGA, and more.

NEW YORK (GenomeWeb) – New thyroid cancer mutations reported recently by members of The Cancer Genome Atlas consortium are already finding their way into at least one sequencing-based genotyping test used to distinguish between benign thyroid nodules and thyroid malignancies.

NEW YORK (GenomeWeb) – A Maryland-based team used real-time, quantitative PCR to screen for human papillomavirus in blood and saliva in order to detect HPV-positive head and neck cancers, track their recurrence, and predict survival patterns.

NEW YORK (GenomeWeb) — An analysis of data from The Cancer Genome Atlas' comprehensive molecular profiling of squamous cell head and neck cancer has revealed a more complicated molecular landscape for the disease, and has identified a new genomic subset that indicates particularly poor survival.

NEW YORK (GenomeWeb) – An integrated molecular analysis of the stomach cancer gastric adenocarcinoma has prompted members of the Cancer Genome Atlas Research Network to put forth four molecular sub-types for the disease.

NEW YORK (GenomeWeb) – Members of the Cancer Genome Atlas today described driver mutations and potential drug targets detected in a common form of lung cancer called lung adenocarcinoma.

NEW YORK (GenomeWeb) — A study of RNA-seq data from several Cancer Genome Atlas cohorts has found that patterns of pseudogene expression correspond strongly with several molecularly or clinically defined cancer subtypes and, in some cases, might offer additional subtyping or prognostic prediction

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Lawmakers have asked four direct-to-consumer genetic testing companies to explain their privacy policies and security measures, according to Stat News.

The Trump Administration has proposed a plan to reorganize the federal government, the Washington Post reports.

In Science this week: genetic overlap among many psychiatric disorders, and more.

The Economist writes that an increasing number of scientific journals don't do peer review.