stem cells
Late-Onset Alzheimer's Disease Features Thwarted by Protective Variant
A homozygous version of the Christchurch variant appeared to reduce disease-related features in mouse models and cells containing a late-onset Alzheimer's-linked APOE4 mutation.
Stem Genomics, Pluristyx Partner for Pluripotent Stem Cell Products, Services
The partners will offer customers a unified pathway to evaluate the genomic stability of pluripotent stem cell lines.
Blood-Based MRD Testing Identifies AML Patients at Risk of Relapse After Stem Cell Transplant
Researchers looked at AML variants in the blood of patients prior to their allogeneic hematopoietic cell transplant and correlated them with subsequent relapse or death.
Cardiac-Related Consequences of Alcohol Flushing Genetic Variant Reduced by Drug
With endothelial cells derived from induced pluripotent stem cells, researchers tracked functional changes and potential treatment targets in alcohol flushing variant carriers.
Five research groups participating in the NHGRI-funded Molecular Phenotypes of Null Alleles in Cells initiative aim to characterize 1,000 null alleles in a pilot phase.