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stem cells

Using CRISPR mouse and iPS cell models, the researchers showed that a rare maternally inherited variant is a genetic modifier of two paternally inherited variants.

By sequencing several individuals with unexplained pancreas and brain development problems, investigators identified a recurrent missense mutation in the CNOT1 gene.

To See More Clearly

Nature News reports that researchers in Japan hope to soon test the use of reprogrammed stem cells to treat damaged corneas.

The pharma and biotech company said it plans to use the genome editing technology in its bioproduction products and services and in stem cells for research.

Researchers were able to estimate the number of active hematopoietic stem cells based on the number of somatic mutations present.

Researchers in Japan being a new trial of induced pluripotent stem cells to treat Parkinson's disease, Science reports.

The two studies used Drop-seq RNA profiling to discover essentially all cell types and establish cell lineages in a model organism flatworm. 

Kyoto University investigator has been fired for research misconduct, while Nobel Laureate Shinya Yamanaka has been penalized for lack of oversight, Retraction Watch reports.

This Week in PNAS

In PNAS this week: a DNA repair map for Saccharomyces cerevisiae, an in vitro method for genetic mapping in hybrid mammals, and more. 

Will They Renew?

As the California Institute for Regenerative Medicine runs out of funds, NPR asks whether states will again fund stem cell research.

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US National Institutes of Health Director Francis Collins says he will avoid male-only speaker panels.

Two patients fell ill, and one subsequently died, following a fecal microbiome transplant that harbored multi-drug-resistant bacteria, according to the New York Times.

Technology Review reports that eGenesis is testing whether organs from genetically modified pigs can be transplanted into monkeys.

In Science this week: almond reference genome, and more.