stem cells

The results suggest patients receiving stem cell transplants for blood cancers may be at increased risk of somatic mutation-related complications even with young bone marrow donors.

The assets include intellectual property relevant to iPSC-based phenotypic drug discovery and an existing product business around iPSC-derived cells.

The partners will offer drug discovery services based on human induced pluripotent stem cells and cells derived from these.

Researchers characterized new and known cell populations with single-cell transcriptome profiles for nearly 10,400 liver cells, using the data to see changes associated with liver cancer.

Using CRISPR mouse and iPS cell models, the researchers showed that a rare maternally inherited variant is a genetic modifier of two paternally inherited variants.

By sequencing several individuals with unexplained pancreas and brain development problems, investigators identified a recurrent missense mutation in the CNOT1 gene.

The pharma and biotech company said it plans to use the genome editing technology in its bioproduction products and services and in stem cells for research.

Researchers were able to estimate the number of active hematopoietic stem cells based on the number of somatic mutations present.