protein-protein interaction networks

Using pathway and network analyses, researchers identified overlapping genes and biological processes behind smoking and schizophrenia, including new candidate genes.

Genome Canada and its partners recently funded two new initiatives with C$255 that will back precision medicine, genomics, and technology development.

The Danish informatics firm is exploring analytical tools for its InWeb_InBioMap network, which currently contains more than 700,000 protein-protein interactions. 

Researchers get a clear image of the DROSHA protein and gain a better understanding of the Microprocessor complex involved in miRNA biogenesis. 

The work offers a proof of concept for the notion that dynamic models of signaling could serve as more effective biomarkers than discrete molecular markers.

Researchers develop a method to capture protein-protein interactions as well as to gauge how frequently they occur and their strength.

Harvard researchers have developed a model of human protein-protein interactions that they said can be used to study interactome organization.

DSysMap combines mutation information with protein interaction data to provide a clearer picture of functional changes associated with the development of complex diseases.

Researchers have developed a mathematical framework for forming disease modules based on protein interaction profiles and GWAS data.

PLA image

In a study, the method was able to detect the interaction of EGFR with an associated signaling protein and predict response to targeted therapies.

Pages

The New York City medical examiner is overseeing an effort to identify missing persons using DNA, according to the Associated Press.

Nobel laureate Günter Blobel has died at 81, the New York Times reports.

In PNAS this week: mouse model of genetically induced emphysema, gene expression signatures of circulating melanoma cells, and more.

Technology Review reports that 2017 was the year of consumer genetic testing and that it could spur new analysis companies.