The system, called EvolvR, can continuously diversify all nucleotides within a tunable window at user-defined loci using CRISPR-guided nickases.
Using pathway and network analyses, researchers identified overlapping genes and biological processes behind smoking and schizophrenia, including new candidate genes.
Genome Canada and its partners recently funded two new initiatives with C$255 that will back precision medicine, genomics, and technology development.
The Danish informatics firm is exploring analytical tools for its InWeb_InBioMap network, which currently contains more than 700,000 protein-protein interactions.
Researchers get a clear image of the DROSHA protein and gain a better understanding of the Microprocessor complex involved in miRNA biogenesis.
The work offers a proof of concept for the notion that dynamic models of signaling could serve as more effective biomarkers than discrete molecular markers.
Researchers develop a method to capture protein-protein interactions as well as to gauge how frequently they occur and their strength.
Harvard researchers have developed a model of human protein-protein interactions that they said can be used to study interactome organization.
DSysMap combines mutation information with protein interaction data to provide a clearer picture of functional changes associated with the development of complex diseases.
Researchers have developed a mathematical framework for forming disease modules based on protein interaction profiles and GWAS data.
A genome-wide association study highlights a potential role for hair follicles in acne risk, according to New Scientist.
Newsday reports that breast cancer genetic testing guidelines for are out of date and may miss individuals.
In Cell this week: gene editing-based strategy to screen for immune system regulators, ancient plague patterns, and more.
Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.