protein-protein interaction networks Disease-Linked Mutations May Affect Protein-Protein Interactions, Influence Drug Response Both germline variants and somatic tumor variants linked to disease are more likely to disrupt protein-protein interactions than other variants. Scipher Medicine, Galapagos Sign IBD Drug Development Deal The companies will jointly validate novel drug targets identified by Scipher's molecular interaction network platform for patients with inflammatory bowel disease. Scipher Medicine to Launch PrismRA Anti-TNF Response Predictor Following Positive Data Publication Premium The gene expression test retrospectively identified rheumatoid arthritis patients significantly less likely to respond to TNF inhibitor therapy. Nautilus Biotechnology Closes $76M Series B Financing Round The startup aims to develop a low-cost, high-throughput proteomics platform that combines biochemistry with computer science and information technology. Tens of Thousands of Protein-Protein Interactions Reported in Human Reference Interactome Map The protein-protein interactions tallied in the project are expected to inform future studies of biology and disease in various tissue and cell types. Jan 9, 2019 Scipher Medicine Builds Evidence for Tests Predicting Response to Autoimmune Disease Drugs Premium Aug 1, 2018 Researchers Develop Tool for Rapid Evolution of Useful Phenotypes in Cells Feb 13, 2018 Study Explores Genetic Overlap Between Nicotine Addiction, Schizophrenia Feb 1, 2018 Newly Funded Genome Canada Projects Focus on Proteomics, Rare Disease, Crop Genomics Premium Dec 8, 2017 Intomics Expands Protein Interaction Offering as Collaborators Report Cancer Driver Prediction Tool Premium Dec 31, 2015 IBS Researchers See DROSHA for First Time Dec 30, 2015 Researchers Model JNK Signaling to Predict Survival in Neuroblastoma Premium Jul 16, 2015 Researchers Develop New Protein-Protein Interaction Network to Explore Human Interactome Mar 4, 2015 IRB Barcelona's dSysMap Combines Mutation, Protein Structure Data to Improve Disease Studies Premium Feb 20, 2015 Computational Approach Extracts Complex Disease Insights from Incomplete Protein Interaction Network Premium Jan 15, 2015 Proximity Ligation Assays Show Potential to Detect Altered EGFR Signaling, Predict Drug Response Premium Dec 15, 2014 Pan-Cancer Study Points to Gene Networks Prone to Rare Mutations in TCGA Tumors Nov 20, 2014 Researchers Present Map of Human Protein-Protein Interactions Premium Jul 12, 2013 Toronto Team Hoping New ABC Transporter Interaction Map Will Support Drug Research, Other Clinical Efforts Premium Breaking News Ancient DNA Analysis Highlights Three Ancestral Populations in Japan FDA Warns of Potential False Positives With Abbott SARS-CoV-2 Molecular Tests New Products Posted to GenomeWeb: Oxford Nanopore, Beckman Coulter, Thermo Fisher Scientific, More People in the News: New Appointments at Sema4, NHGRI, Dante Labs, Ancestry, More Thermo Fisher Scientific Expects 12 Percent Revenue Growth in 2022 In Brief This Week: Myriad Genetics, Danaher, Co-Diagnostics, and More The Scan For Those Thick Tiger Stripes Tigers in India with thick stripes harbor a genetic change, as Gizmodo reports. High GABA Tomatoes The Japan News reports that genome-edited tomatoes with higher GABA levels are now for sale in Japan. Approach for Inclusivity and Diversity A National Human Genome Research Institute team calls for the field to "adopt diversity as an ethos." Science Papers on Tumors Immune System Evasion; Drivers of Genomic Instability, Inflammation In Science this week: study of how tumors evade the adaptive immune system, and more.