PIK3CA Roche Nabs CE Mark for PIK3CA Test for Breast Cancer The PCR-based test detects mutations in the PIK3CA gene that can cause cells to grow uncontrollably, possibly leading to cancer. Mutations in FOXA1 Gene Can Affect Breast Cancer Patients' Response to Therapy A new study found that FOXA1 missense mutations were enriched in metastatic breast tumors and Guardant360 Results in Alpelisib Trial Suggest Liquid Biopsy May Help Better Capture Non-Responders Premium A study of both tissue and blood samples from patients in a small trial found that liquid biopsy may detect putative resistance mutations missed in tissue. Genetron Health Obtains Regulatory Approval in China for NGS Instrument, Lung Cancer Panel The high-throughput S2000 sequencer is the second instrument Genetron Health has received NMPA approval for, following the S5 benchtop instrument last year. Qiagen Obtains CE Mark for PIK3CA Mutation Assay Qiagen obtained CE marking for its Therascreen PIK3CA RGQ PCR kit to aid in identifying breast cancer patients with a PIK3CA mutation. Nov 19, 2019 Double Mutations in PIK3CA Gene Increase Patient Sensitivity to Targeted Therapies, Study Finds Premium Oct 18, 2019 Cervical Cancer Exomes Point to Potentially Targetable HER, PIK3CA Pathway Changes May 24, 2019 FDA Approves Qiagen's PIK3CA Test as Companion Test for Novartis Breast Cancer Drug Dec 18, 2018 Cancer Genetic Studies Explore Prognostic Value of Copy Number Alterations, Other Biomarkers Premium Dec 7, 2018 Novartis Drug Shows Promise in PIK3CA Mutated Breast Cancer, Potential Utility of ctDNA Testing Premium Dec 6, 2018 Qiagen to Develop Companion Dx for Novartis Breast Cancer Drug Oct 30, 2018 Precision Oncology Highlights From ESMO 2018 Jun 3, 2018 ASCO Study Shows Modest Efficacy of PI3 Kinase Inhibitor in Molecularly Defined Breast Cancer Premium Jun 3, 2018 NCI-MATCH Researchers Discuss First Data From Three Treatment Arms at ASCO Premium Dec 9, 2016 Novartis PI3K Inhibitor Effective in Breast Cancer Subset; Psych Toxicities Dampen Enthusiasm Premium Dec 11, 2014 Phase II Study Shows ER/PR Status, Not PIK3CA Mutations, May ID Responders to PI3K Inhibitor Premium Dec 18, 2013 As Molecular Understanding of HER2-Positive Breast Cancer Advances, New Treatment Strategies Emerge Premium Mar 1, 2012 Randox Molecular Diagnostics Strategy Takes Shape with Pending Launch of Three New Tests Premium Aug 18, 2011 As it Readies US Lab, Germany's Inostics Moving Beyond Service Model with Digital PCR Tech Premium Jun 1, 2011 Transgenomic Hopes to Attract Pharma Partners with Exclusive License to PIK3CA/PTEN PGx Testing Premium Apr 14, 2011 Product Watch: Apr 14, 2011 Premium Breaking News In Brief This Week: Illumina, Personalis, Proteomedix, and More Ancient DNA Details Population Dynamics Within Andean Tiwanaku Civilization Genomic Data Spanning 2K Years Gives Glimpse of Etruscan Origins, Population Changes People in the News: New Appointments at Hologic, Akoya Biosciences, Caris Life Sciences, More At NSGC, Genetic Counselors Address Race-Based Medicine, Ways to Change New Products Posted to GenomeWeb: Becton Dickinson, Cosmos-ID, OncoDNA, More The Scan US Booster Eligibility Decision The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions. Arizona Bill Before Judge The Arizona Daily Star reports that a judge weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction. Additional Genes Wales is rolling out new genetic testing service for cancer patients, according to BBC News. Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.