PI3K
Breast Cancer Study Shows Number of Mutated PIK3CA Alleles Affects Tumor Aggressiveness
Studies in breast tumors revealed a "biphasic" relationship between mutant PIK3CA allele dosage and stem cell-like features as well as aggressiveness.
Roche Nabs CE Mark for PIK3CA Test for Breast Cancer
The PCR-based test detects mutations in the PIK3CA gene that can cause cells to grow uncontrollably, possibly leading to cancer.
Mutations in FOXA1 Gene Can Affect Breast Cancer Patients' Response to Therapy
A new study found that FOXA1 missense mutations were enriched in metastatic breast tumors and
BostonGene Partners With Dana-Farber's Weinstock Lab on T-Cell Lymphoma Biomarker Research
The company will provide proprietary algorithms for analyzing omics and imaging data to define predictors of drug response and identify new biomarkers.
Double Mutations in PIK3CA Gene Increase Patient Sensitivity to Targeted Therapies, Study Finds
Premium
Researchers found that about 12 percent to 15 percent of breast cancer patients carry multiple mutations in the gene, 95 percent of which are double mutations.