Mycobacterium tuberculosis

The study is the first to demonstrate the design features and operational characteristics of Cepheid's Xpert MTB/RIF Ultra assay.

Researchers discussed using WGS to predict antibacterial resistance, to inform influenza vaccine development, and to diagnose and build drug resistance profiles for tuberculosis.

The database of genotype, phenotype, and clinical data from multi-drug resistant TB cases may support improved diagnostic development and clinical decision making.

The gift is from a group of more than 20 philanthropists and will be used to develop a rapid diagnostic test for drug-resistant TB. 

The tool uses whole genome sequence from M. tuberculosis strains to predict genetic resistance to tuberculosis drugs faster than traditional culture-based methods.

The new clearance allows the use of the Xpert MTB/RIF test, in conjunction with other clinical or laboratory data, to remove patients from respiratory isolation.

NEW YORK (GenomeWeb News) – Harvard Medical School and Columbia University have both received grants from the National Institute of Allergy and Infectious Diseases, totaling $12.3 million this year, to create translational research centers to develop molecular diagnostics technologies.

NEW YORK (GenomeWeb News) – Researchers at the Swiss Federal Institute of Technology have developed a tool to single out specific proteins contained within the Mycobacterium tuberculosis proteome.

NEW YORK (GenomeWeb News) – CLC bio has been awarded a $2 million grant from the European Union to develop a software platform to support a multi-partner project using next-generation sequencing to identify infections, the company said today.

NEW YORK (GenomeWeb News) – Epistem said today that Becton Dickinson will distribute the firm's Mycobacterium tuberculosis test on a global basis, excluding India and the Indian Sub-Continent.

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.