Researchers brought together blood transcriptomic, metabolomic, proteomic, and immune cell profiles for dozens of West African and Australasian infants.
Using pathway and network analyses, researchers identified overlapping genes and biological processes behind smoking and schizophrenia, including new candidate genes.
A genomic analysis of ependymomas from 42 patients led to nearly 1,700 suspected super enhancers, highlighting potentially targetable genes.
The work offers a proof of concept for the notion that dynamic models of signaling could serve as more effective biomarkers than discrete molecular markers.
The proof-of-principle application suggests networks of microRNA, RNA, and other 'omics data can untangle drug response and more.
The firms are integrating their technology platforms for drug discovery applications.
Webb Miller, Trey Ideker, Patrick Soon-Shiong
Now in its ninth year, the experiment that was the Institute for Systems Biology has become an established research organization known for its focus on translational science.
Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.
St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.
St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.
In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.