methylation

Researchers from St. Jude Children's and the German Cancer Research Center used methylation and gene expression analyses to uncover the subtypes.

The approach can increase CpG coverage about 18-fold by inferring from existing data to predict methylation of sites outside those covered on the arrays themselves.

The researchers said that the methylation mark could potentially be used as a noninvasive biomarker for certain tumor types. 

The company presented its findings last week at the 2016 Gastrointestinal Cancer Symposium and is preparing to launch the assay in the US later this year.

In Genome Biology this week: genetic and environmental influence on human methylome variation, brackish water microbiome, and more.

A team of Austrian researchers has developed a high-throughput pipeline to uncover and analyze DNA methylation without relying on a reference genome.

Researchers identified DNA methylation patterns associated with both historical and current lifestyles and environments in Central African individuals.

The results could inform diagnosis and treatment for PTSD and PTSD-associated and inflammation-associated disorders.

At the AMP meeting this week, JHU's Sara Sukumar discussed efforts to adapt a cell-free methylated DNA assay for breast cancer to a Cepheid Xpert cartridge.

The researchers demonstrated the approach by visualizing DNA methylation changes in distal non-coding regulatory regions in mouse embryonic cells.

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Sometimes genetic tests give inconclusive results and provide little reassurance to patients, the Associated Press reports.

Vox wonders whether gene-editing crops will be viewed similarly as genetically modified organisms of if people will give them a try.

In Science this week: research regulation and reporting requirement reform, and more.

With H3Africa, Charles Rotimi has been working to bolster the representation of African participants and African researchers in genomics, Newsweek reports.