Researchers examined DNA methylation and chromatin accessibility in preimplantation embryos using single-cell chromatin overall omic-scale landscape sequencing.
The team demonstrated that the approach can yield high sensitivity while maintaining near-perfect specificity, but it must now replicate the early results in a much larger study.
The American Cancer Society today lowered the recommended age for screening patients at average risk for the disease to 45 from 50 years old.
Researchers found that individuals with unexplained neurodevelopmental disorders and congenital anomalies had an enrichment of de novo epivariations.
With genome-wide association study data, researchers saw enrichment for schizophrenia-linked SNPs in human-specific differentially methylated regions.
In Nature this week: ash dieback disease fungal genome, and more.
The researchers didn't find overall methylation differences between infants who later developed autism and those who did not.
In Genome Biology this week: peopling of the Sahara, epigenetic reprogramming analysis of liverwort, and more.
Investigators identified mutation, expression, and methylation differences in colorectal polyps from individuals with or without colorectal cancer.
Whitehead Institute researchers were able to restore nearly full FMR1 expression in a fragile X syndrome iPSC cell line.
Though many details have yet to be worked out, the draft deal for the UK's withdrawal from the EU is giving researchers some hints for what they can expect, Nature News says.
DNA testing has solved a 100-year-old mystery contained in the skull and teeth samples of a now-extinct monkey that once inhabited Jamaica, Gizmodo reports.
As the UN ponders a ban on gene drives, one malaria researcher says there are less dramatic ways to fight the disease in Africa than unleashing GM mosquitoes on a whole continent.
In Nature this week: an improved reference genome of the Aedes aegypti mosquito, genomes of four species of truffles, and more.