methylation

The company's validation studies demonstrate that the assay has a 99 percent negative predictive value, which it believes will persuade physicians of its value.

This Week in Cell

In Cell this week: DNA methylation and T cell exhaustion, longevity in C. elegans, and more.

This Week in PNAS

In PNAS this week: DNA methylation profiles of tumor tissue, gene dynamics in prokaryotes, and more.

Under the terms of the deal, MDxHealth and QUT will evaluate and develop the test, which will evaluate abnormal DNA methylation changes.

The test, which detects DNA methylation markers, is being developed as an alternative to invasive cystoscopy, the current standard of care.

The technology is based on the work of UCLA's Steve Horvath, who has shown that DNA methylation age could predict all-cause mortality later in life.

The investment bank gave Exact Sciences' shares a price target of $30, and said it expects higher uptake of the Cologuard test and an increase in payor contracts. 

The computational method, called DeepCpG, is designed to tease out missing epigenetic marks and related DNA motifs in single-cell DNA methylation data.

The University of California, Los Angeles-led team said the approach outperformed two established classification methods.

MethylCap-seq data for dozens of primary endometrioid endometrial cancers led to a 13-region methylation signature linked to broader tumor genome features.

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Gene drives might run into biological resistance, the Economist reports.

Forensic experts exhumed painter Salvador Dalí's body to collect DNA for a paternity test, CBS News reports.

Yale Environment 360 writes that synthetic and conservation biologists aren't always on the same wavelength, but they are trying to reach an understanding.

In Science this week: full CRISPR locus integration complex structure, and more.