methylation | GenomeWeb

methylation

The University of California, Los Angeles-led team said the approach outperformed two established classification methods.

MethylCap-seq data for dozens of primary endometrioid endometrial cancers led to a 13-region methylation signature linked to broader tumor genome features.

Researchers showed in a new study that patterns of methylation co-occuring at different sites could help distinguish cancer DNA in the blood, and mark its original source in body.

Two research groups reported on statistical methods for uncovering methylated cytosine and/or adenine bases using electrical current cues from Oxford Nanopore sequencers.

An epigenetic analysis showed that the tumors all shared a certain DNA methylation signature, but that methylation patterns varied between samples.

In Genome Biology this week: epigenetic differences in CML cells, predicting aggressive prostate cancer, and more.

The qPCR-based test was shown to differentiate cancerous and non-cancerous tissue and predict biochemical recurrence, and can be used on small, degraded samples. 

This Week in PNAS

In PNAS this week: transcriptional control enables malaria parasite to get around disease control efforts, DNA methylation patterns in the Norway spruce, and more.

Dartmouth researchers characterized 5-methylcytosine and 5-hydroxymethylcytosine marks in more than two dozen glioblastoma samples.

The researchers found that 80 percent of pediatric posterior fossa ependymomas have decreased levels of H3K27me3 histone modifications.

Pages

Ivanka Trump and Secretary of Education Betsy DeVos call on girls to pursue STEM careers, the Associated Press reports.

Some science companies will be taking part in next month's March for Science, Fortune reports.

In Genome Research this week: longitudinal study of Burkholderia cenocepacia isolates from cystic fibrosis patients, long-read assembly approach, and more.

Shale oil companies are turning to DNA sequencing to find spots to drill, Reuters reports.