These differentially variable positions appear to implicate stress response in rheumatoid arthritis development and possibly in other autoimmune conditions.
Using archived tumor samples from individuals with glioblastoma, researchers saw methylation variability at progression, along with potential prognostic hints.
A heterozygous variant upstream of the BRCA1 translation start site was uncovered in all individuals in these two families with hypermethylated BRCA1 promoters.
The company shared early evidence of the potential of its approach to improve newborn screening for immune disorders, and to offer new tools for other areas like HIV monitoring.
The Israeli firm recently announced the results of a multicenter study of its Bladder EpiCheck test in addition to netting €2.5 million in EU funding to develop a lung cancer assay.
With Pacific Biosciences sequencing, researchers found DNA N6-methyladenine modifications in the human genome and noted a role for it in tumorigenesis.
In an epigenome-wide association study of depression, the researchers tied DNA methylation to disease symptoms and suggested a role for axon guidance disruption.
Patients whose tumors had methylated MGMT promoters were more likely to survive than those that did not after combination treatment with radiotherapy and temozolomide.
The UK's Human Fertility and Embryology Authority calls for consumer genetic testing companies to warn customers that testing could uncover family secrets, according to the Guardian.
