methylation

Researchers saw an over-representation of CpG methylation shifts in 11 obesity-related genes in more than 260 adolescents from a Pennsylvania cohort.

The company is developing a methylated DNA biomarker that will predict all-cause mortality risk and risk of developing certain age-related diseases.

The firm believes that data from a recently published study illustrates the advantages of its technology for methylation-specific PCR assays.

In an epigenome-wide association study, researchers uncovered more than 1,000 sex-related differentially methylated positions among chronic lymphocytic leukemia patients.

New research suggests that the physicochemical changes to DNA in a cancer-related methylation landscape can alter a DNA molecule's affinity for gold substrates.

The researchers found that both a SNP and prenatal factors like maternal age influence imprinting at the nc886 gene.

With a DNA methylation atlas and deconvolution algorithm, researchers are attempting to trace cfDNA back to tissue sources in healthy or ill individuals.

Investigators published an initial report on the method, which they call cfMeDIP-Seq, last week, and are now hoping to move to analysis of samples from longitudinal health studies.

The team said it will partner with startup Early Diagnostics to commercialize the assay, which integrates DNA methylation analysis and computational technology.

This Week in PNAS

In PNAS this week: artemisinin resistance mutations in malaria parasites, ant-plant interactions over time, and more.

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The World Health Organization has announced the members of its gene-editing committee, according to NPR.

DARPA is working on developing algorithms that gauge the credibility of research findings, Wired reports.

The American Society of Breast Surgeons recommends all women diagnosed with breast cancer be offered genetic testing, the Washington Post says.

In Science this week: comparison of modern, historical rabbit exomes uncovers parallel evolution after myxoma virus exposure; and more.