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Using transcriptomic, metabolomic, metagenomic, and other data types, a team identified purine metabolism as a potential target for intervention.
Metabolon's Precision Metabolomics platform identifies pharmacodynamic, efficacy, and response biomarkers and tracks changes in biological pathways.
The partners will use ReviveMed's AI-driven platform to better understand mechanisms of immunotherapy response and resistance in cancer patients.
In Cell this week: proteomic and metabolomic analysis of blood from COVID-19 patients, change in phosphorylation with infection, and more.
In Cell this week: catalog of structural variants within the human genome, proteomic and metabolomic profiles of COVID-19 patients' blood, and more.
A method called microbiome-derived metabolism screening highlighted drug alterations after exposure to personalized gut microbe collections.
In PNAS this week: autosomal genes commonly affected by loss-of-function variants, variants implicated in testis development disorders, and more.
Researchers saw a shift toward lower gut bifidobacterial levels and a dip in pro-inflammatory Th17 immune cells due to ketone bodies production.
In PNAS this week: analysis of 1,200 high-coverage Samoan genome sequences, metabolites associated with frailty among the elderly, and more.
If the results are validated, investigators believe the method could help diagnose patients without the need for a needle biopsy and with fewer false positives.
Two COVID-19 vaccine developers have released their trial protocols to build public trust, the New York Times reports.
A new analysis finds the rapid COVID-19 test from DnaNudge to be highly accurate, Reuters reports.
In Science this week: global citizens' assembly on genome-editing technologies proposed, epigenetic markers predict metformin response, and more.
According to the Verge, many US states are not including positive results from rapid COVID-19 testing in their case numbers.
