The new technique, enabled by enzymatic library preparation and a tight bioinformatics pipeline, could have applications in liquid biopsy.
Researchers developed a k-mer-based classification scheme to assay lncRNA function, identifying cis-repressive lncRNAs with k-mer features resembling Xist.
UMich's Arul Chinnaiyan plans to use the funding to develop new tools and technologies to identify biomarkers for cancer diagnosis and treatment.
A deep RNA sequencing analysis of adipose tissue from lean and obese individuals highlighted new and previously annotated human long intergenic noncoding RNAs.
A University of Michigan-led team found that the lncRNA ARLNC1 forms a feedback loop with the androgen receptor to promote progression in prostate cancer.
In a talk at the meeting, Riken's Piero Carninci described the RADICL-seq tool he and his colleagues developed.
In Nucleic Acids Research this week: tool to identify bacterial plasmid sequences, long-read sequencing of Saccharomyces cerevisiae strain, and more.
In Science this week: influence of gut microbiome metabolism on host, and more.
A short pyknon motif on the lncRNA N-BLR appears to mediate its effect on cells' ability to metastasize and invade in colorectal cancer, researchers found.
The FANTOM consortium generated an atlas of nearly 30,000 human long non-coding RNAs that suggests more than 19,000 of them are functional.
The Hill reports President Donald Trump issued an executive directing federal agencies to cut the number of board and advisory committees they have.
The New York Times reports that researchers are combining tools to more quickly develop crops to feed a growing population and cope with shifting climates.
Scientists in Canada are looking to the UK's plan to sequence children with rare conditions for inspiration, the National Post reports.
In PNAS this week: copy number changes arose during polar bear evolution, genomic and transcriptomic analysis of the Siberian hamster, and more.