The transient transcriptome sequencing protocol relies on combining sequencing with 4-thiouridine labeling and RNA fragmentation.
A genome-wide association suggests an African-specific lincRNA allele on chromosome 7 contributes to risk of bloodstream infection by Streptococcus pneumoniae.
In Genome Biology this week: computational approach to tease apart clonal tumor lineages, cell type-specific lncRNA expression in developing human neocortex, and more.
Qiagen has submitted an offer to buy all of Exiqon's shares for DKK18 each, for a total aggregate purchase price of DKK683 million ($103.5 million).
With the help of TCGA sequence data, researchers uncovered expression of a long, non-coding RNA called SAMMSON that appears to be specific to melanoma.
In Genome Biology this week: inter-individual variability of long non-coding RNAs, computational approach for removing low-quality cells from single-cell analyses, and more.
The researchers said that long non-coding RNAs showed more specificity to different cancer types than protein-coding genes, making them important, precise biomarkers.
In Genome Research this week: lncRNA and gene expression regulation, population structure of the equine infectious disease strangles, and more.
In PNAS this week: human cytomegalovirus diversity, patterns of homologous recombination in E. coli, and more.
In PNAS this week: spatiotemporal study of lncRNA expression, role of extrachromosomal, circular DNAs in yeast, and more.
In Science this week: genetic target for urothelial bladder cancer treatment, and more.
At the Conversation, the University of Oxford's Michael Macklay writes that learning genetic risk of disease is a personal decision.
Two dozen scientific organizations have endorsed the March for Science, according to ScienceInsider.
Researchers in Japan describe a chimpanzee with a chromosomal abnormality similar to human Down syndrome, Mashable reports.