A short pyknon motif on the lncRNA N-BLR appears to mediate its effect on cells' ability to metastasize and invade in colorectal cancer, researchers found.
A genome-wide association suggests an African-specific lincRNA allele on chromosome 7 contributes to risk of bloodstream infection by Streptococcus pneumoniae.
In Genome Biology this week: computational approach to tease apart clonal tumor lineages, cell type-specific lncRNA expression in developing human neocortex, and more.
With the help of TCGA sequence data, researchers uncovered expression of a long, non-coding RNA called SAMMSON that appears to be specific to melanoma.
In Genome Biology this week: inter-individual variability of long non-coding RNAs, computational approach for removing low-quality cells from single-cell analyses, and more.
The researchers said that long non-coding RNAs showed more specificity to different cancer types than protein-coding genes, making them important, precise biomarkers.
