long non-coding RNAs
While short-read sequencing is still essential for studying RNA and gene expression, new methods are providing a sharper picture of transcript variants.
NCI Grants $1.9M to Roswell Park to Study Molecular Race-Based Breast Cancer Disparities
The grant will fund an investigation into long noncoding RNA and the role it plays in differing prognoses between Black and white breast cancer patients.
A new sequencing-based method developed by Duke University's Kate Meyer is one of several that can detect RNA methylation without the use of antibodies.
Stanford Researchers Map RNA Localization Within Cells Using New Spatial Transcriptomics Method
APEX-seq builds on a proteomic labelling technique and offers a new spatial genomics tool for looking at the life of transcripts within the cell.
The new technique, enabled by enzymatic library preparation and a tight bioinformatics pipeline, could have applications in liquid biopsy.